Just discovered a cheat for gen 2.

[Vixi]

I'm not sure if this is already on Bulbapedia (I had a brief look) nor do I know where to add it (Pokemon Stadium 2 page maybe?).

I just discovered a cheat for gen 2 that lets you obtain additional Pokemon before Poke Balls are available and before fighting ???. It requires 2 games, Pokemon Stadium 2 and 2 Transfer Paks.
I'm not sure if this works before obtaining the Pokedex (Only thought of trying it after I got the Pokedex)

Step 1: Save in the Cherrygrove Pokemon Center
Step 2: Put the game and another game into Transfer Paks and start up PS2
Step 3: Trade your starter Pokemon for anything you like from the other game (eg a level 100 Mewtwo to completely obliterate ???'s Pokemon)
Optional a: Make sure the Pokemon you are receiving is holding a Poke Ball, you can use the Ball to catch another Pokemon.
Optional b: Trade both your Pokemon for 2 more Pokemon holding Balls, catch more Pokemon and repeat untill you have the team you desire.

Enjoy bringing 6 level 100 legendaries or whatever Pokemon team you feel like to the fight against ???

I used this trick to trade my Chikorita for my level 6 Shiny Pikachu from my other game and beat ???'s Cyndaquil easily with Surf.

 

[SnorlaxMonster]

So essentially, trading in high-level stuff early in the game makes it easier (although you are ignoring disobedience). That's really not worthwhile noting.